Fagerberg, E., Attanasio, J., Dien, C., Singh, J., Kessler, E.A., Abdullah, L., Shen, J., Hunt, B.G., Connolly, K.A., De Brouwer, E., He, J., Iyer, N.R., Buck, J., Borr, E.R., Damo, M., Foster, G.G., Giles, J.R., Huang, Y.H., Tsang, J.S., Krishnaswamy, S., Cui, W., Joshi, N.S. 2025. KLF2 maintains lineage fidelity and suppresses CD8 T cell exhaustion during acute LCMV infection. Science. 2;387(6735):eadn2337.
Strine, M.S., Fagerberg, E., Darcy, P.W., Barron, G.M., Filler, R.B., Alfajaro, M.M., D’Angelo-Gavrish, N., Wang, F., Graziano, V.R., Menasché, B.L., Damo, M., Wang, Y., Howitt, M.R., Lee, S., Joshi, N.S., Mucida, D., Wilen, C.B. 2024. Intestinal tuft cell immune privilege enables norovirus persistence. Sci Immunol 10.1126/sciimmunol.adi7038.
Damo, M., Hornick, N.I., Venkat, A., William, I., Clulo, K., Venkatesan, S., He, J., Fagerberg, E., Loza, J.L., Kwok, D., Tal, A., Buck, J., Cui, C., Singh, J., Damsky, W.E., Leventhal, J.S., Krishnaswamy, S., and N.S. Joshi. 2023. PD-1 maintains CD8 T cell tolerance towards cutaneous neoantigens. Nature 10.1038/s41586-023-06217-y.
- Highlighted in Nature Immunology News & Views, July 2023
Kasmani, M., Zander, R., Chung, H.K., Chen, Y., Khatun, A., Damo, M., Topchyan, P., Johnson, K., Levashova, D., Burns, R., Lorenz, U., Tarakanova, V., Joshi, N.S., Kaech, S., and W. Cui. 2023. Clonal lineage tracing reveals mechanisms skewing CD8+ T cell fate decisions in chronic infection. J Exp Med 220(1):e20220679.
Connolly, K.A., Fitzgerald, B., Damo, M., and N.S. Joshi. 2022. Novel Mouse Models for Cancer Immunology. Annu Rev Cancer Biol 6(1):269-291.
Cui, C., Wang, J., Fagerberg, E., Chen, P., Connolly, K.A., Damo, M., Cheung, J.F., Mao, T., Askari, A.S., Chen, S., Fitzgerald, B., Foster, G.G., Eisenbarth, S.C., Zhao, H., Craft, J., and N.S. Joshi. 2021. Neoantigen-driven B cell and CD4 T follicular helper cell collaboration promotes anti-tumor CD8 T cell responses. Cell 184(25):6101-6118.e13.
Connolly, K.A., Kuchroo, M., Venkat, A., Khatun, A., Wang, J., William, I., Hornick, N., Fitzgerald, B., Damo, M., Kasmani, M.Y., Cui, C., Fagerberg, E., Monroy, I., Hutchins, A., Cheung, J.F., Foster, G.G., Mariuzza, D.L., Zhao, H., Cui, W., Krishnaswamy, S., and N.S. Joshi. 2021. A reservoir of stem-like CD8 T cells in the tumor-draining lymph node preserves the ongoing anti-tumor immune response. Sci Immunol 6, eabg7836.
Damo, M.*, Fitzgerald, B.*, Lu, Y., Nader, M., William, I., Cheung, J.F., Connolly, K.A., Foster, G.G., Akama-Garren, E., Lee, D., Chang, G.P., Gocheva, V., Schmidt, L.M., Boileve, A., Wilson, J.H., Cui, C., Monroy, I., Gokare, P., Cabeceiras, P., Jacks, T., and N.S. Joshi. 2021. Inducible de novo expression of neoantigens in tumor cells and mice. Nat Biotechnol 39(1):64-73.
Damo, M.*, Wilson, D.S.*, Watkins, E.A., and J.A. Hubbell. Soluble N-Acetylgalactosamine-modified antigens enhance hepatocyte-dependent antigen cross-presentation and result in antigen-specific CD8+ T cell tolerance development. 2021. Front Immunol 12:555095.
Wilson, D.S.*, Damo, M.*, Hirosue, S., Raczy, M.R., Brunggel, K., Diaceri, G., Quaglia-Thermes, X., and J.A. Hubbell. 2019. Synthetically glycosylated antigens induce antigen-specific tolerance and prevent the onset of diabetes. Nat Biomed Eng 3:817-829.
Damo, M., and N.S. Joshi NS. 2019. Treg cell IL-10 and IL-35 exhaust CD8+ T cells in tumors. Nat Immunol 20(6):674-675.
Ishihara, J., Ishihara, A., Potin, L., Hosseinchi, P., Fukunaga, K., Damo, M., Gajewski, T., Swartz, M., and J.A. Hubbell. 2018. Improving Efficacy and Safety of Agonistic Anti-CD40 Antibody Through Extracellular Matrix Affinity. Mol Cancer Therapeutics 17(11):2399-2411.
Damo, M., Wilson, D.S., Simeoni, E., and J.A. Hubbell. 2015. TLR-3 stimulation improves anti-tumor immunity elicited by dendritic cell exosome-based vaccines in a murine model of melanoma. Sci Rep 5:17622.
Lombardo, A., Cesana, D., Genovese, P., Di Stefano, B., Provasi, E., Colombo, D.F., Neri, M., Magnani, Z., Cantore, A., Lo Riso, P., Damo, M., Pello, O.M., Holmes. M.C., Gregory, P.D., Gritti, A., Broccoli, V., Bonini, C., and L. Naldini. 2011. Site-specific integration and tailoring of cassette design for sustainable gene transfer. Nat Methods 8:861-869.
Matrai, J., Cantore, A., Bartholomae, C.C., Annoni, A., Wang, W., Acosta-Sanchez, A., Samara-Kuko, E., De Waele, L., Ma, L., Genovese, P., Damo, M., Arens, A., Goudy, K., Nichols, T.C., von Kalle, C., Chuah, M.K., Roncarolo, M.G., Schmidt, M., Vandendriessche, T., and L. Naldini. 2011. Hepatocyte-targeted expression by integrase-defective lentiviral vectors induces antigen-specific tolerance in mice with low genotoxic risk. Hepatology 53(5):1696-707.
Strine, M.S., Fagerberg, E., Darcy, P.W., Barron, G.M., Filler, R.B., Alfajaro, M.M., D’Angelo-Gavrish, N., Wang, F., Graziano, V.R., Menasché, B.L., Damo, M., Wang, Y., Howitt, M.R., Lee, S., Joshi, N.S., Mucida, D., Wilen, C.B. 2024. Intestinal tuft cell immune privilege enables norovirus persistence. Sci Immunol 10.1126/sciimmunol.adi7038.
Damo, M., Hornick, N.I., Venkat, A., William, I., Clulo, K., Venkatesan, S., He, J., Fagerberg, E., Loza, J.L., Kwok, D., Tal, A., Buck, J., Cui, C., Singh, J., Damsky, W.E., Leventhal, J.S., Krishnaswamy, S., and N.S. Joshi. 2023. PD-1 maintains CD8 T cell tolerance towards cutaneous neoantigens. Nature 10.1038/s41586-023-06217-y.
- Highlighted in Nature Immunology News & Views, July 2023
Kasmani, M., Zander, R., Chung, H.K., Chen, Y., Khatun, A., Damo, M., Topchyan, P., Johnson, K., Levashova, D., Burns, R., Lorenz, U., Tarakanova, V., Joshi, N.S., Kaech, S., and W. Cui. 2023. Clonal lineage tracing reveals mechanisms skewing CD8+ T cell fate decisions in chronic infection. J Exp Med 220(1):e20220679.
Connolly, K.A., Fitzgerald, B., Damo, M., and N.S. Joshi. 2022. Novel Mouse Models for Cancer Immunology. Annu Rev Cancer Biol 6(1):269-291.
Cui, C., Wang, J., Fagerberg, E., Chen, P., Connolly, K.A., Damo, M., Cheung, J.F., Mao, T., Askari, A.S., Chen, S., Fitzgerald, B., Foster, G.G., Eisenbarth, S.C., Zhao, H., Craft, J., and N.S. Joshi. 2021. Neoantigen-driven B cell and CD4 T follicular helper cell collaboration promotes anti-tumor CD8 T cell responses. Cell 184(25):6101-6118.e13.
Connolly, K.A., Kuchroo, M., Venkat, A., Khatun, A., Wang, J., William, I., Hornick, N., Fitzgerald, B., Damo, M., Kasmani, M.Y., Cui, C., Fagerberg, E., Monroy, I., Hutchins, A., Cheung, J.F., Foster, G.G., Mariuzza, D.L., Zhao, H., Cui, W., Krishnaswamy, S., and N.S. Joshi. 2021. A reservoir of stem-like CD8 T cells in the tumor-draining lymph node preserves the ongoing anti-tumor immune response. Sci Immunol 6, eabg7836.
Damo, M.*, Fitzgerald, B.*, Lu, Y., Nader, M., William, I., Cheung, J.F., Connolly, K.A., Foster, G.G., Akama-Garren, E., Lee, D., Chang, G.P., Gocheva, V., Schmidt, L.M., Boileve, A., Wilson, J.H., Cui, C., Monroy, I., Gokare, P., Cabeceiras, P., Jacks, T., and N.S. Joshi. 2021. Inducible de novo expression of neoantigens in tumor cells and mice. Nat Biotechnol 39(1):64-73.
Damo, M.*, Wilson, D.S.*, Watkins, E.A., and J.A. Hubbell. Soluble N-Acetylgalactosamine-modified antigens enhance hepatocyte-dependent antigen cross-presentation and result in antigen-specific CD8+ T cell tolerance development. 2021. Front Immunol 12:555095.
Wilson, D.S.*, Damo, M.*, Hirosue, S., Raczy, M.R., Brunggel, K., Diaceri, G., Quaglia-Thermes, X., and J.A. Hubbell. 2019. Synthetically glycosylated antigens induce antigen-specific tolerance and prevent the onset of diabetes. Nat Biomed Eng 3:817-829.
Damo, M., and N.S. Joshi NS. 2019. Treg cell IL-10 and IL-35 exhaust CD8+ T cells in tumors. Nat Immunol 20(6):674-675.
Ishihara, J., Ishihara, A., Potin, L., Hosseinchi, P., Fukunaga, K., Damo, M., Gajewski, T., Swartz, M., and J.A. Hubbell. 2018. Improving Efficacy and Safety of Agonistic Anti-CD40 Antibody Through Extracellular Matrix Affinity. Mol Cancer Therapeutics 17(11):2399-2411.
Damo, M., Wilson, D.S., Simeoni, E., and J.A. Hubbell. 2015. TLR-3 stimulation improves anti-tumor immunity elicited by dendritic cell exosome-based vaccines in a murine model of melanoma. Sci Rep 5:17622.
Lombardo, A., Cesana, D., Genovese, P., Di Stefano, B., Provasi, E., Colombo, D.F., Neri, M., Magnani, Z., Cantore, A., Lo Riso, P., Damo, M., Pello, O.M., Holmes. M.C., Gregory, P.D., Gritti, A., Broccoli, V., Bonini, C., and L. Naldini. 2011. Site-specific integration and tailoring of cassette design for sustainable gene transfer. Nat Methods 8:861-869.
Matrai, J., Cantore, A., Bartholomae, C.C., Annoni, A., Wang, W., Acosta-Sanchez, A., Samara-Kuko, E., De Waele, L., Ma, L., Genovese, P., Damo, M., Arens, A., Goudy, K., Nichols, T.C., von Kalle, C., Chuah, M.K., Roncarolo, M.G., Schmidt, M., Vandendriessche, T., and L. Naldini. 2011. Hepatocyte-targeted expression by integrase-defective lentiviral vectors induces antigen-specific tolerance in mice with low genotoxic risk. Hepatology 53(5):1696-707.